Takenaka Y, Inoue I, Nakano T, Shinoda Y, Ikeda M, Awata T, Katayama S.
A Novel Splicing Variant of Peroxisome Proliferator-Activated Receptor-γ (Pparγ1sv) Cooperatively Regulates Adipocyte Differentiation with Pparγ2
PLoS ONE (8:e65583) (2013 Jun)

Kayo Fujimaki-Aoba, Shinji Komazaki, Philip J Jensik, Shigeru Hokari and Makoto Takada.
Larval bullfrog skin lacks amiloride-blockable epithelial transpot because α-ENaC is located within intracellular vesicles in epidermal apical cells and not in the apical plasma membrane.
Acta Histochemica (2013), 115(1):357-362.

Norihiro Kotani, Yoshihito Ishiura, Ryusuke Yamashita, Tomoko Ohnishi and Koichi Honke.
Fibroblast growth factor receptor 3 (FGFR3) associated with the CD20 antigen regulates the Rituximab-induced proliferation inhibition in B-cell lymphoma cells.
J. Biol. Chem (2012), 287:37109-37118.

Noboru Hashimoto, Kazunori Hamamura, Norihiro Kotani, Keiko Furukawa, Kei Kaneko, Koichi Honke and Koichi Furukawa
Proteomic analysis of ganglioside-associated membrane molecules: Substantial basis for molecular clustering.
Proteomics (2012), 12: 3154-3163.

Songlin Jiang, Norihiro Kotani, Tomoko Ohnishi, Arisa Miyagawa-Yamguchi, Masayuki Tsuda, Ryusuke Yamashita, Yoshihito Ishiura and Koichi Honke.
A proteomics approach to the cell-surface interactome using the enzyme-mediated activation of radical sources reaction.
Proteomics (2012), 12: 54-62.

Makoto Seo, Ryo Kobayashi, Tetsunori Okamura, Koji Ikeda, Masahiko Satoh, Naoki Inagaki, Hiroichi Nagai and Hisamitsu Nagase.
Enhancing effects of trichloroethylene and tetrachloroethylene on type I allergic responses in mice.
J. Toxicol. Sci (2012), 37(2): 439-445.

Koichi Honke and Norihiro Kotani.
Identification of cell-surface molecular interactions under living conditions by using the enzyme-mediated activation of radical sources (EMARS) method.
Sensors (2012), 12(12): 16037-16045.

本家孝一、小谷典弘
生細胞膜上の分子間相互作用解析試薬「EMARS試薬Ar-Flu」の開発
バイオインダストリー (2012), 29(9): 37-42.

穂苅茂（分担: 第６章　核酸）
栄養科学イラストレイテッド　生化学ノート　改訂第２版（薗田勝　編）
羊土社 (2012), ISBN978-4-7581-0888-1

【2011年度】

Makoto Seo, Ryo Kobayashi, Hisamitsu Nagase J Health Sci. Immunotoxic effects of trichloroethylene and tetrachloroethylene., 57, 488-496, 2011.(Review)

Takanari Nakano, Masanori Matsui, Ikuo Inoue, Takuya Awata, Shigehiro Katayama, Takayuki Murakoshi. Free immunoglobulin light chain: Its biology and implications in diseases, Clinica Chimica Acta, 412: 843-849 (2011)

Yuko Kaneko, Kayo Fujimaki-Aoba, Shu-ichi Watanabe, Shigeru Hokari, Makoto Takada. Localization of ENaC subunit mRNAs in adult bullfrog skin. Acta Histochemica, 114(2), 172-176 (2012 Feb)

【2010】

Ikeda T, Seo M, Inoue I, Katayama S, Matsunaga T, Hara A, Komoda T and Tabuchi M: Direct and simple fluorescence detection method for oxidized lipoproteins. Anal Chem 2010 Feb 82(3): 1128-1132.

Takahashi S, Inoue I, Nakajima Y, Seo M, Nakano T, Yang F, Kumagai M, Komoda T, Awata T, Ikeda M and Katayama S: A promoter in the novel exon of hPPARgamma directs the circadian expression of PPARgamma. J Atheroscler Throm 2010 Feb 17(1): 73-83.

【2009】

Nakano T, Inoue I, Katayama S, Seo M, Takahashi S, Hokari S, Shinozaki R, Hatayama K, Komoda T. Lysophosphatidylcholine for efficient intestinal lipid absorption and lipoprotein secretion in Caco-2 cells. Journal of Clinical and Biochemical Nutrition 45(2):227-34. (2009)

Nakano T, Inoue I, Shinozaki R, Matsui M, Akatsuka A, Takahashi S, Tanaka K, Akita M, Seo M, Hokari S, Katayama S, Komoda T：A possible role of lysophospholipids produced by calcium-independent phospholipase A2 in membrane-raft budding and fission. Biochimica et Biophysica Acta – Biomembranes  1788:2222-8 (2009)

Nakano T, Inoue I, Alpers DH, Akiba Y, Katayama S, Shinozaki R, Kaunitz JD, Ohshima S, Akita M, Takahashi S, Koyama I, Matsushita M, Komoda T.: Role of lysophosphatidylcholine in brush border intestinal alkaline phosphatase release and restoration. American Journal of Physiology ; Gastrointestinal and liver physiology 297(1):G207-14 (2009)

Nakano T, Inoue I, Seo M, Takahashi S, Awata T, Komoda T, Katayama S: Rapid and simple profiling of lipoproteins by polyacrylamide-gel disc electrophoresis to determine the heterogeneity of low-density lipoproteins (LDLs) including small-dense LDL. Recent Patent Cardiovascular Drug Discovery 4(1):31-6 (2009)

Nakano T,Inoue I, Satoh K, Yamazaki M, Awata T, Kurihara S, Goto S, Shinoda Y, Komoda T, Katayama S: Treatment with glimepiride, but not mitiglinide and short-acting insulin, resists body weight and abdominal fat reduction under dietary energy-restriction. Journal of atherosclerosis and thrombosis 16(1):63-6 (2009)

Nakano T, Inoue I, Seo M, Takahashi S, Awata T, Komoda T, Katayama S.：Rapid and simple profiling of lipoproteins by polyacrylamide-gel disc electrophoresis to determine the heterogeneity of low-density lipoproteins (LDLs) including small, dense LDL. Recent Pat Cardiovasc Drug Discov. 2009 Jan;4(1):31-6.

Takada M, Fujimaki-Aoba K, Hokari S: Effects of arginine vasotocin and mesotocin on the activation and development of amiloride-blockable short-circuit current across larval, adult, and cultured larval bullfrog skins. J Comp Physiol B. 2010 Mar;180(3):393-402. Epub 2009 Dec 1.

Takahashi S, Inoue I, Nakajima Y, Seo M, Nakano T, Yang F, Kumagai M, Komoda T, Awata T, Ikeda M, Katayama S. A promoter in the novel exon of hPPARg directs the circadian expression PPARg (in press). Journal of atherosclerosis and thrombosis  (2009)

Sasa M, Inoue I, Shinoda Y, Takahashi S, Seo M, Komoda T, Awata T, Katayama S.:Activating effect of momordin, extract of bitter melon (Momordica Charantia L.), on the promoter of human PPARdelta. J Atheroscler Thromb. 2009;16(6):888-92. Epub 2009 Dec 22.

瀬尾誠，永瀬久光: 有機塩素系溶剤によるアレルギー反応増悪化に関する研究 岐阜薬科大学紀要 2009 Jun; 58: 9-18.

【2008】

Kawaguchi T, Nakano T, Sasagawa K, Ohashi T, Miura T, Komoda T.：Tartrate-resistant acid phosphatase 5a and 5b contain distinct sugar moieties. Clin Biochem. 2008 Oct;41(14-15):1245-9. Epub 2008 Jul 30.

Niikawa M, Chuuriki K, Shibuya K, Seo M and Nagase H: Effect of aspirin on chromosome aberration and DNA damage induced by X-ray in mice. Radiation Effects and Defects on Solids 2008 Jul; 163: 655-660.

Takada M, Fujimaki K, Hokari S.：Vasotocin has the potential to inhibit basolateral Na+/K+-pump current across isolated skin of tree frog in vitro, via its V2-type receptor/cAMP pathway. J Comp Physiol B. 2008 Nov;178(8):957-62. Epub 2008 Jun 7.

Seo M, Yamagiwa T, Kobayashi R, Ikeda K, Satoh M, Inagaki N, Nagai H, Nagase H.：A small amount of tetrachloroethylene ingestion from drinking water accelerates antigen-stimulated allergic responses. Immunobiology. 2008;213(8):663-9. Epub 2008 Apr 2.

Seo M, Yamagiwa T, Kobayashi R, Ikeda K, Satoh M, Inagaki N, Nagai H, Nagase H.：Augmentation of antigen-stimulated allergic responses by a small amount of trichloroethylene ingestion from drinking water. Regul Toxicol Pharmacol. 2008 Nov;52(2):140-6. Epub 2008 Aug 3.

Seo M, Ikeda K, Okamura T, Kida K, Satoh M, Inagaki N, Nagai H, Nagase H.：Enhancing effect of chlorinated organic solvents on histamine release and inflammatory mediator production. Toxicology. 2008 Jan 14;243(1-2):75-83. Epub 2007 Sep 29.

Seo M, Inoue I, Ikeda M, Nakano T, Takahashi S, Katayama S, Komoda T. ：Statins Activate Human PPARalpha Promoter and Increase PPARalpha mRNA Expression and Activation in HepG2 Cells. PPAR Res. 2008;2008:316306. Epub 2008 Dec 24.

【2007】
Matsushita M, Irino T, Kamiyama K, Muramoto Y, Kawaguchi T, Nakano T, Komoda T.：Evaluation of a method for measuring tissue non-specific alkaline phosphatase activity in healthy subjects. Ann Clin Biochem. 2007 Nov;44(Pt 6)：544-548.

Nakano T, Seo M, Komoda T, Kitazato KT, Uno M, Hamaoki M, Nagata A.：Immunoreactive circulating oxidized HDL concentrations do not increase in patients undergoing carotid endarterectomy: a comparative study for oxidized HDL and oxidized LDL concentrations in plasma. Clin Chim Acta. 2007 Jun;381(2):179-81. Epub 2007 Mar 19. No abstract available.

Nakano T, Inoue I, Koyama I, Kanazawa K, Nakamura K, Narisawa S, Tanaka K, Akita M, Masuyama T, Seo M, Hokari S, Katayama S, Alpers DH, Millán JL, Komoda T.：Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1439-49. Epub 2007 Mar 1.

Takada M, Hokari S.：Prolactin increases Na+ transport across adult bullfrog skin via stimulation of both ENaC and Na+/K+-pump. Gen Comp Endocridol. 2007 May 1;151(3):325-331.

【2006】

Inoue I, Shinoda Y, Nakano T, Sassa M, Goto S, Awata T, Komoda T, Katayama S.：Acarbose ameliorates atherogenecity of low-density lipoprotein in patients with impaired glucose tolerance.. Metabolism. 2006.07. 55(7)：946-952

Shinoda Y, Inoue I, Nakano T, Seo M, Sassa M, Goto S, Awata T, Komoda T, Katayama S.：Acarbose improves fibrinolytic activity in patients with impaired glucose tolerance.. Metabolism. 2006.07. 55(7)：935-939

Nakano T, Miyazaki S, Takahashi H, Matsumori A, Maruyama T, Komoda T, Nagata A.：Immunochemical quantification of free immunoglobulin light chains from an analytical perspective.. Clin Chem Lab Med. 2006.05. 44(5)：522-532

Takada M, Shimomura T, Hokari S, Philip J. Jensik, Thomas C.Cox：Larval bullfrog skin expresses ENaC despite having no amiloride-blockable transepithelial Na＋ transport.  J.Comparative Physiology ­－ B, 176, 287-293 (2006)

Nakano T, Takahashi H, Miyazaki S, Kawai S, Shinozaki R, Komoda T, Nagata A.：Antigen-specific free immunoglobulin light chain antibody: Could it be a new diagnostic marker for patients with allergy? Clinical Biochemistry 39:955-959.(2006)

Nakano T, Miyazaki S, Shinoda Y, Inoue I, Katayama S, Komoda T, Nagata A.：Proposed reference material for human free immunoglobulin light chain measurement. Journal of Immunoassay and Immunochemistry 27: 129-37. (2006)

Nakano T, Shimanuki T, Matsushita T, Koyama I, Inoue I, Katayama S, Alpers DH, Komoda T.：Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and their association with ABO and secretor blood group types. Biochemical and Biophysical Research Communications  340: 1317–1322. (2006)

【2005】

Nakano T, Nataga A.：Oxidative susceptibility of apolipoprotein AI in serum. Clinica Chimica Acta  362:119-124.(2005)

Nakano T, Kamei Y.：In vivo antiviral activity of interferon b production-promoting fraction from a marine brown alga, Sargassum hemipyllum. Botanica Marina  48: 84-6.(2005)

【2004】
Nakano T, Nataga A.：ELISAs for free human immunoglobulin light chain in serum: improvement of assay specificity by using specific antibodies in a sandwich detection method. Journal of Immunological Methods  293:183-189. (2004)

Nakano T, Nagata A, Takahashi H.：Ratio of urinary free immunoglobulin light chain kappa to lambda in the diagnosis of Bence Jones proteinuria. Clinical Chemistry and Laboratory Medicine  42:429-434 (2004)

Miyazaki T, Matsunaga T, Miyazaki S, Hokari S, Komoda T.：Changes in receptor activator of nuclear factor-kappaB, and its ligand, osteoprotegerin, bone-type alkaline phosphatase, and tartrate-resistant acid phosphatase in ovariectomized rats. J Cell Biochem. 2004 Oct 15;93(3):503-12.

Koyama I, Matsunaga T, Harada T, Kikuno A, Hokari S, Komoda T.：Ambroxol reduces LPS toxicity mediated by induction of alkaline phosphatases in rat lung.
Clin Biochem. 2004 Aug;37(8):688-93.

Nakajima T, Matsunaga T, Kawai S, Hokari S, Inoue I, Katayama S, Nagata A, Komoda T.：Characterization of the epitopes specific for the monoclonal antibody 9F5-3a and quantification of oxidized HDL in human plasma. Ann Clin Biochem. 2004 Jul;41(Pt 4):309-15.

【2003】

Nakano T, Matsunaga S, Nataga A, Maruyama T.：NAD(P)H oxidase p22phox Gene C242T polymorphism and lipoprotein oxidation. Clinica Chimica Acta 335:101-107.(2003)

Nakano T, Nagata A. Immunochemical detection of circulating oxidized high-density lipoprotein with antioxidized apolipoprotein A-I monoclonal antibody. Journal of Laboratory and Clinical Medicine  141(6):378-84.(2003)

Nakano T, Nagata A.：ELISAs for free light chains of human immunoglobulins using monoclonal antibodies: comparison of their specificity with available polyclonalantibodies. Journal of Immunological Methods 275(1-2):9-17.(2003)

Hokari S, Miura K, Koyama I, Kobayashi M, Matsunaga T, Iino N, Komoda T.：
Expression of alpha-amylase isozymes in rat tissues.　Comp Biochem Physiol B Biochem Mol Biol. 2003 May;135(1):63-9.

Matsunaga T, Hokari S, Koyama I, Harada T, Komoda T.：NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein. Biochem Biophys Res Commun. 2003 Mar 28;303(1):313-9.

Hokari S, Miyazaki T, Matsunaga T, Kawai S, Koyama I, Komoda T.：Rabbit liver dCMP phosphohydrolase: a pyrimidine 5'-nucleotidase I-like enzyme in non-erythrocytic cells.　Comp Biochem Physiol B Biochem Mol Biol. 2003 Feb;134(2):381-8.

Matsunaga T, Nakajima T, Miyazaki T, Koyama I, Hokari S, Inoue I, Kawai S, 　Shimomura H, Katayama S, Hara A, Komoda T.：Glycated high-density lipoprotein regulates reactive oxygen species and reactive nitrogen species in endothelial cells.　Metabolism. 2003 Jan;52(1):42-9.

【2002】

Ohnishi K, Hokari S, Shutou H, Ohshima M, Furuichi N, Goda M.：Origin of most primitive mRNAs and genetic codes via interactions between primitive tRNA ribozymes.　Genome Inform. 2002;13:71-81.

Matsunaga T, Koyama I, Hokari S, Komoda T.：Detection of oxidized high-density lipoprotein.　J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Dec 5;781(1-2):331-43. Review.

Koyama I, Matsunaga T, Harada T, Hokari S, Komoda T.：Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation.　Clin Biochem. 2002 Sep;35(6):455-61.

Koyama I, Komine S, Hokari S, Matsunaga T, Nakamura KI, Komoda T.：Electrophoretically unique amylases in rat livers: phylogenic and ontogenic study on the mammalian liver.　Electrophoresis. 2002 Sep;23(19):3278-83.

Miyazaki T, Matsunaga T, Miyazaki S, Hokari S, Komoda T.：Characterization of  four monoclonal antibodies to recombinant human tartrate-resistant acid phosphatase. Hybrid Hybridomics. 2002 Jun;21(3):191-5.

Hokari S, Miura K, Koyama I, Kobayashi M, Komine S, Komoda T.：A restriction endonuclease assay for expression of human alpha-amylase isozymes. Clin Chim  Acta. 2002 Aug;322(1-2):113-6.

Kawai S, Nakajima T, Hokari S, Komoda T, Kawai K.：Apolipoprotein A-I concentration in tears in diabetic retinopathy.　Ann Clin Biochem. 2002 Jan;39(Pt 1):56-61.

Oh-ie K, Miyazaki T, Koyama I, Hokari S, Komoda T.：Altered bone turnover in chlorpromazine-challenged rats and its effect on 1alpha-hydroxyvitamin D3 administration in vivo.　J Bone Miner Metab. 2002;20(1):21-7. 

【2001】

Hokari S, Miyazaki T, Matsunaga T, Koyama I, Hasegawa M, Komoda T.：      Expression of pyrimidine 5'-nucleotidase subclass I during erythrocyte maturation in rats. J Hematother Stem Cell Res. 2001 Oct;10(5):703-7.

Matsunaga T, Iguchi K, Nakajima T, Koyama I, Miyazaki T, Inoue I, Kawai S, Katayama S, Hirano K, Hokari S, Komoda T.：Glycated high-density lipoprotein induces apoptosis of endothelial cells via a mitochondrial dysfunction. Biochem Biophys Res Commun. 2001 Sep 28;287(3):714-20.

Hokari S, Miyazaki T, Hasegawa M, Koyama L, Komoda T.：Chicken erythrocyte pyrimidine 5'-nucleotidase: purification and characterization of the subclass I enzyme. Biol Chem. 2001 Jun;382(6):919-24.

Matsunaga T, Nakajima T, Sonoda M, Koyama I, Kawai S, Inoue I, Katayama S, Hirano K, Hokari S, Komoda T.：Modulation of reactive oxygen species in endothelial cells by peroxynitrite-treated lipoproteins. J Biochem. 2001 Aug;130(2):285-93.

Koyama I, Komine S, Iino N, Hokari S, Igarashi S, Alpers DH, Komoda T.：alpha-Amylase expressed in human liver is encoded by the AMY-2B gene identified in tumorous tissues.　Clin Chim Acta. 2001 Jul 5;309(1):73-83.

Koyama I, Komine S, Hokari S, Yakushijin M, Matsunaga T, Komoda T.：Expression of alpha-amylase gene in rat liver: liver-specific amylase has a high affinity to glycogen.　Electrophoresis. 2001 Jan;22(1):12-7.

Inoue I, Goto S, Matsunaga T, Nakajima T, Awata T, Hokari S, Komoda T, Katayama S.：The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells.　Metabolism. 2001 Jan;50(1):3-11.

【2000】

Koyama I, Komine S, Yakushijin M, Hokari S, Komoda T.：Glycosylated salivary alpha-amylases are capable of maltotriose hydrolysis and glucose formation.　Comp Biochem Physiol B Biochem Mol Biol. 2000 Aug;126(4):553-60.

Inoue I, Goto S, Mizotani K, Awata T, Mastunaga T, Kawai S, Nakajima T, Hokari S, Komoda T, Katayama S.：Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. Life Sci. 2000 Jul 14;67(8):863-76.

Nakajima T, Origuchi N, Matsunaga T, Kawai S, Hokari S, Nakamura H, Inoue I, Katayama S, Nagata A, Komoda T.：Localization of oxidized HDL in atheromatous plaques and oxidized HDL binding sites on human aortic endothelial cells. Ann Clin Biochem. 2000 Mar;37 ( Pt 2):179-86.

Nakajima Y, Yamagishi T, Hokari S, Nakamura H.：Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP). Anat Rec. 2000 Feb 1;258(2):119-27. Review.