准教授、医局長 横田 和浩 YOKOTA, Kazuhiro リウマチ性疾患、膠原病、臨床免疫学 専門資格： 日本内科学会認定内科医・総合内科専門医・指導医、日本リウマチ学会専門医・指導医

原著論文

• Yokota K, Ohtake A, Yamazaki T, Wada TT, Tsuruoka SM, Fushimi T, Murayama K, Akiyama Y, Mimura T.
  Carbamoyl phosphate synthetase 1 deficiency manifested in an adult treated with prednisone for polymyositis, and cured by live-donor liver transplantation.
  Molecular Genetics and Metabolism Reports 2025 Mar 5:43:101200. doi: 10.1016/j.ymgmr.2025.101200. eCollection 2025 Jun.PMID: 40125546
• Yokota K.
  Osteoclast Differentiation in Rheumatoid Arthritis
  Immunological Medicine. 2024 Mar;47(1):6-11. doi: 10.1080/25785826.2023.2220931. Epub 2023 Jun 13. PMID: 37309864
• Yokota K, Morimoto K, Yazawa H, Wada TT, Sakamoto T, Terui Y, Kaneko S, Inoue T, Okada H, Akiyama Y, Mimura T.
  Successful Treatment of Diffuse Large B-cell Lymphoma Involving Multiple Renal and Bone Infiltrations Presenting with Giant Cell Arteritis-like Manifestations: A Case Report
  Internal Medicine. 2024 Jun 1;63(11):1645-1652. doi: 10.2169/internalmedicine.2377-23. Epub 2023 Nov 13. PMID: 37952957
• Yokota K, Tachibana H, Miyake A, Yamamoto T, Mimura T.
  Relapsing Polychondritis and Aseptic Meningoencephalitis.
  Internal Medicine. 2022 Jul 14. doi: 10.2169/internalmedicine.9411-22. Online ahead of print.
• Yokota K, Noma H, Tarumoto N, Ishibashi N, Sakai J, Maesaki S, Iida S, Uchida Y, Uchida T, Nakayama H, Haga Y, Mimura, T.
  A Retrospective Observational Cohort Study on the Efficacy and Safety of Methylprednisolone Pulse Therapy for COVID-19 Pneumonia.
  COVID 2(3):244-253. 2022.
• Yokota K, Sato K, Miyazaki T, Aizaki Y, Tanaka S, Sekikawa M, Kozu N, Kadono Y, Oda H, Mimura T.
  Characterization and Function of Tumor Necrosis Factor alpha and Interleukin-6-Induced Osteoclasts in Rheumatoid Arthritis.
  Arthritis & Rheumatology 73(7):1145-1154. 2021.
• Yokota K, Tsuzuki Wada T, Akiyama Y, Mimura T.
  Detection of synovial inflammation in rheumatic diseases using superbmicrovascular imaging: Comparison with conventional power Doppler imaging.
  Modern Rheumatology 28(2):327-333. 2018.
• Yokota K.
  Inflammation and osteoclasts.
  Japanese Journal of Clinical Immunology 40:367-376. 2017.
• Yokota K, Kishida D, Kayano H, Yazaki M, Shimada Y, Akiyama Y, Mimura T.
  A Case of Abdominal Aortic Retroperitoneal and Mesenteric Amyloid Light Chain Amyloidoma.
  Case Reports in Rheumatology 2016:4146030. Epub Sep 26. 2016.
• Yokota K, Inoue T, Akiyama Y, Kajiyama H, Asanuma FY, Arai E, Suzuki H, Mimura T.
  Acute kidney injury in polyarteritis nodosa and multiple myeloma.
  Internal Medicine 53(3):263-7. 2014.
• Yokota K, Sato K, Miyazaki T, Kitaura H, Kayama H, Miyoshi F, Araki Y, Akiyama Y, Takeda K, Mimura T.
  Combination of tumor necrosis factor α and interleukin 6 induces osteoclast-like cells with bone-resorption activity both in vitro and in vivo.
  Arthritis & Rheumatology 66(1):121-9. 2014.
• Yokota K, Miyazaki T, Hemmatazad H, Gay RE, Kolling C, Fearon U, Suzuki H, Mimura T, Gay S, Ospelt C.
  The Pattern-Recognition Receptor NOD1 Promotes Production of Inflammatory Mediators in Rheumatoid Arthritis Synovial Fibroblasts.
  Arthritis & Rheumatism 64(5):1329-37. 2012.
• Yokota K, F. Miyoshi, K. Sato, Y. Asanuma, Y. Akiyama, T. Mimura.
  Geranylgeranyl-pyrophosphate Regulates Secretion of Pentraxin 3 and Monocyte Chemoattractant Protein-1 from Rheumatoid Fibroblast-like Synoviocytes in Distinct Manners.
  Clinical and Experimental Rheumatology 29(1):43-9. 2011.
• Yokota K, Akiyama Y, Adachi D, Shindo Y, Yoshida Y, Miyoshi F, Arai E, Kuramochi A, Tsuchida T, Mimura T.
  Subcutaneous panniculitis-like T-cell lymphoma accompanied by Sjögren's syndrome.
  Scandinavian Journal of Rheumatology 38(6):494-5. 2009.
• Yokota K, Akiyama Y, Asanuma Y, Miyoshi F, Sato K, Mimura T.
  Efficacy of tacrolimus in infliximab-refractory progressive rheumatoid arthritis.
  Rheumatology International 29(4):459-61. 2009.
• Yokota K, Akiyama Y, Sato K, Shindo Y, Yoshida Y, Miyoshi F, Akiba H, Nakajima K, Asanuma Y, Akiyama Y, Mimura T.
  Vasculo-Behçet’s Disease with Non-traumatic Subcapsular Hematoma of the Kidney and Aneurysmal Dilatations of the Celiac and Superior Mesenteric Arteries.
  Modern Rheumatology 18(6):615-8. 2008.
• Yokota K, Miyoshi F, Miyazaki T, Sato K, Yoshida Y, Asanuma Y, Akiyama Y, Mimura T.
  High Concentration Simvastatin Induces Apoptosis in Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis.
  Journal of Rheumatology 35(2):193-200. 2008.
• Yokota K, Miyazaki T, Hirano M, Akiyama Y, Mimura T.
  Simvastatin Inhibits Production of IL-6 and IL-8 and Cell Proliferation Induced by TNF-α in the Fibroblast-Like Synoviocytes from Rheumatoid Arthritis Patients.
  Journal of Rheumatology 33(3):463-71. 2006.
• Yokota K, Hirano M, Akiba H, Adachi D, Takeishi M, Akiyama Y, Mimura T.
  A case of Behcet's disease with esophageal ulcers complicated with systemic sclerosis, chronic hepatitis C, and pancytopenia.
  Japanese Journal of Clinical Immunology 27:164-70. 2004.

受賞歴

• 令和3年度　埼玉医科大学医師会 研究奨励賞
• 令和2年度　武田科学振興財団 研究奨励賞
• 平成28年度 日本リウマチ学会 奨励賞
• 平成28年度 埼玉医科大学病院 優秀指導医賞
• 平成27年度 埼玉医科大学 第26回落合記念賞
• 平成27年度 日本リウマチ学会 国際ワークショップ賞
• 平成26年度 東京生化学研究会 研究奨励賞
• 平成26年度 埼玉医科大学病院 優秀指導医賞
• 平成20年度 埼玉医科大学 第19回落合記念賞